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They worsen progressively without any improvement trend
The Adjusted R 2 value, considering the degrees of freedom and sample size, is calculated as 0.9607
[DOI] [PMC free article] [PubMed] [Google Scholar] 95.Rae C.D., Williams S.R
This necessitates a dual strategy: first, advancing treatments that modulate convergent downstream pathologies (e.g., TDP-43 homeostasis, neuroinflammation) common across ALS forms
