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Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain. This study reported on the brain tissue of individuals with autism, finding evidence of oxidative stress and inflammation associated with a low glutathione redox status

312,313,314,315,316,317 MSCs achieve neuroprotection by directly releasing or increasing the release of endogenous neurotrophic factors, such as BDNF, NGF, GDNF and bFGF

Moreover, systemic comorbidities highly relevant to human periodontitis, such as diabetes, obesity, smoking, or agerelated immune senescence, are absent from most standard models despite their known effects on inflammatory networks, bone metabolism, and treatment outcomes [102]
Lephart ED, Naftolin F