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In 1957, Margoshes and Vallee discovered low-molecular-mass sulfhydryl-rich proteins, the metallothioneins (MTs) [10]

The 4-hydroxyestrogen SG, NacCys, and Cys conjugates had the same MRM transitions as the 2-hydroxyestrogens did, and these metabolites were, therefore, separated only by chromatographic retention

Engineered solely for preclinical investigations, each batch of Dihexa undergoes a comprehensive quality assessment and includes complete documentation, including a Certificate of Analysis (COA), purity data, and structural verification

10.1038/s42003-020-0957-6 171 WenC.LiF.ZhangL.DuanY.GuoQ.WangW.et al