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Such continuous cognitive effort, accompanied by a sustained metabolic activity, may eventually induce endogenous oxidative stress (through a sustained generation of ROS during energy production
10.1002/art.23223 Arthritis Rheumatism 29 HarrisonN
Pb has been shown to activate astrocytes and microglia, leading to the release of pro-inflammatory cytokines such as interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-) [99]
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