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In HGSOC-2, we observed oxidative phosphorylation, nucleotide metabolism, N-glycan metabolism, and cholesterol biosynthesis to be upregulated
Further work revealed that G6PD inhibition also modulates calcium stores to promote precontracted vascular smooth muscle relaxation by decreasing calcium influx and increasing sequestration as well as inhibiting Rho kinase (2)
Step 2: decarboxylation The 3-keto-6-phosphogluconate formed is highly unstable and undergoes a spontaneous decarboxylation, resulting in: the formation of CO 2 (from C-1 of the original glucose 6-phosphate)
(591) Abdolmaleki, F
