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Tirzepatide can promote weight loss and support metabolic health by controlling these factors

This strategy is particularly compelling as the activity of these autoinhibitory factors is increased in obesity, hinting at an etiological role for them in leptin resistance [15, 48,49]

Body fat measurement through calipers, bioelectrical impedance, or DEXA scanning provides the most direct fat loss data

Some patients stay on one medication alone, some add a second later in either direction, and some remain on both because the combination continues to feel effective and appropriate for them
