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Exercise is a type of structured activity, such as swimming, cycling, or Pilates
For instance, some phytochemicals can activate the Nrf2 pathway, a master regulator of cellular antioxidant defenses, leading to enhanced protection against oxidative stress
It follows that UCP2 gene variants associated with lower UCP2 protein levels, and therefore less protection against ROS and oxidative stress, could also be linked to these cardiometabolic diseases
Smith et al ., 2018)
