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Josh Bloom expertly explained, Tylenol "has a low therapeutic index, which means that the difference between an effective dose and a toxic dose is small." Indeed, it is relatively easy to accidentally overdose on acetaminophen

In our model, T-cell depletion is preceded by a failure of CD4 T-cell activation and response, as CD4 T cells are essential for maintaining CD8 T-cell cytotoxic responses [230]

FIGURE 5 Sorted cells display elevated gene overexpression level We further demonstrated the cell sorting strategy in a gene overexpression experiment

[DOI] [PMC free article] [PubMed] [Google Scholar] 201.Chen D., Ding Y., Chen G., Sun Y., Zeng X., Ye H