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Hematoxylin and eosin (H&E) and Safranin O staining demonstrated extensive destruction of trabecular architecture and marrow necrosis in femoral head tissues from GC-induced ONFH patients, markedly exceeding the pathological changes observed in non-ONFH controls (Fig

However, this process still faces several technical bottlenecks, mechanistic controversies, and challenges related to therapeutic adaptability

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Shi HA, Wang ZQ, Xu FJ, et al