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Description
All evidence comes from rodent models, cell cultures, or ex vivo tissue samples
Generally well-tolerated in human trials at research doses with no major safety concerns reported [19]
The serum test measures all B12 present in the blood, as well as all substances that are chemically similar to vitamin B12
Paradoxically, the restoration of blood flow during reperfusion exacerbates the injury through mechanisms involving oxidative stress, inflammation, and endothelial dysfunction [3]
