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Cell 159 , 15911602 (2014)

Key Takeaways Creatine powers short bursts of high-intensity activity, while L-carnitine supports fat burning during longer exercise Creatine has superior safety with no major side effects, but L-carnitine may increase cardiovascular risk through TMAO production Choose creatine for strength, power, and muscle growth choose L-carnitine for endurance and fat loss goals Creatine offers cognitive benefits beyond physical performance, making it more versatile for overall health What are Creatine and L-Carnitine