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As glutamate can be converted into glutamine by IECs, although at limited rates, the effects observed for glutamate may be attributable to the effects of glutamine
found increased DNA methylation levels on several CpG nucleotides upstream of miR-4715-3p in upper gastrointestinal adenocarcinoma (UGC) tissue samples, which binds to the 3' untranslated region (3' UTR) of Aurora kinase A (AURKA) to inhibit its expression[120]

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