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doi: 10.1016/j.tibs.2015.12.001 8 FrauwirthKARileyJLHarrisMHParryRVRathmellJCPlasDRet al

Alcohols metabolic interference delays THC-COOH excretion, prolongs subacute fatigue, and disrupts homeostasis restoration

Structure and properties of carotenoids in relation to function

Points against their use depend on the side effects due to the deep suppression of estrogen production, like hot flashes and bone loss, often needing the use of add-back therapy for long treatments (when more than 6 months long), consisting of supplementation of hormones to reduce these negative consequences [66]
