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Description
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2 Intestinal barrier plays a critical role in maintaining gut homeostasis The intestinal barrier is a host protective entity composed of physical and functional barriers (Peterson and Artis, 2014

Celastrol ( 26 , Figure 11 ) is a quinone methide triterpenoid isolated from Celastrus orbiculatus , and showed inhibitory effects against TNF--, IKK-, or MEKK1-mediated NF-B activation on the basis of NF-B luciferase activity [145]

doi:10.1111/j.2042-7158.2010.01167.x 80
