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Supplementing with B12 may lead to improved mood and a reduced risk of mood disorders

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The animals were maintained under standard housing conditions at 22C 2C with 12/12-h light/dark cycles

as a key regulator of mitochondrial biogenesis, PGC1 enhances mitochondrial function in myoblasts, supplies sufficient energy for differentiation, and regulates the transcription of myogenic genes to accelerate myotube maturation
