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The most robust effort to date, an analysis of over 1,000 tumors across 10 tumor subtypes using CPTAC proteogenomics data, identified that mutations in Keap1 and NRF2 were associated with diminished IFN and CD8 T cells [62]

Astrocyte IKK/NF-B signaling is required for diet-induced obesity and hypothalamic inflammation

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Pavan ME, Lpez NI, Pettinari MJ