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This would explain the particular vascular effect and recovery [1,2,3,4,5,6,7,8,9,10] that may take part in eye and glaucoma therapy, as evidenced by particular effects on NO-agents in eye studies [11,12,13,14,15,16,17]

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As the extent of their methylation was much lower in the brain and in lower passage astrocytes, the authors concluded that their high methylation may just be an in vitro artifact of the prolonged passaging of cells (Meissner et al., 2008), a phenomenon that was previously observed (Shen et al., 2006