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These dietary antioxidants or anti-inflammatory nutrients may influence hearing health by regulating the expression of autophagy-related genes (e.g., LC3-II, Beclin-1) and inhibiting key proteins in apoptotic signaling pathways (e.g., caspase-3, Bax), thus preventing cell apoptosis (55)

doi: 10.2147/NDT.S199746, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 66.Mori K, Obara Y, Moriya T, Inatomi S, Nakahata N

The gut microbiota and its metabolites play a pivotal role in high-altitude adaptation by modulating the host immune system through multiple mechanisms ( 3.2.1 Mitigation of oxidative stress Certain gut microbiota and their metabolites enhance the defense of the gut mucosal barrier by alleviating excessive oxidative stress

Ginsenoside Rg3 suppresses mast cell-mediated allergic inflammation via mitogen-activated protein kinase signalling pathway
