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It lies between the blood and the vessel wall, is synthesized and secreted by vascular endothelial cells, and is a dynamic natural barrier that is principally composed of proteoglycans, membrane glycoproteins, and plasma proteins, of which proteoglycans and glycoproteins are the main components (16)

Redox Biol 22:101157

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Lee J, Kang ES, Kobayashi S, Homma T, Sato H, Seo HG, Fujii J (2017) The viability of primary hepatocytes is maintained under a low cysteineglutathione redox state with a marked elevation in ophthalmic acid production