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Inhibition of this pathway in combination with anti-PD-L1 antibody treatment has been shown to reduce infiltration of blood-derived CD45 high /CD11b + macrophages and decrease PD-L1 protein expression in microglia, leading to improved survival in GBM-bearing mice resistant to TMZ 37
Human mutation, 13(5), 362375.[PubMed] [Wiley] Scalise V, Balia C, Cianchetti S, et al
