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Description
Selective c-Met inhibitors have a very high selectivity (more than ten thousand times) for c-Met compared to other kinases [155]
Not everyone benefits from split dosing
Schmerzlinderung : Reduzierte Beschwerden bei chronischen Schmerzen
In addition, daratumumab has been conjugated to DOTA for radiolabeling with the alpha-emitter actinium-225 ( 225 Ac), showing potent CD38-positive tumor cell-killing in vitro and enhanced anti-tumor activity (~ 30-fold) in vivo without significant side effects [131]
