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4B), whereas the SOD activity of HUVECs was below the detection limit (Fig

Dysregulation of endocrine FGF signaling, particularly FGF19 and FGF21, has been implicated in metabolic disease, suggesting their potential as therapeutic mechanisms (4346)

3.3 Metabolic fingerprinting analysis Metabolic fingerprinting is an untargeted metabolomics approach based on chromatographic profiles and MS peaks information that might correlate to chemical compounds through annotation

The liver, heart, and kidney predominantly utilize the malate-aspartate shuttle, whereas, adipose tissue, skeletal muscle, and brain predominantly utilize the glycerol phosphate shuttle