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Tesamorelin is therefore the uniquely positioned research compound for investigating whether and how the complete GHRH(1-44) sequence produces pharmacologically distinct GHRHR biology relative to truncated GHRH analogues and a comparative pharmacology question with direct implications for understanding the physiological role of the C-terminal GHRH domain

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Neuron 21(4):695705 Li Y, Wu H, Khardori R, Song Y-H, Lu YW, Geng Y-J (2009) Insulin-like growth factor-1 receptor activation prevents high glucose-induced mitochondrial dysfunction, cytochrome-c release and apoptosis

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