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In a randomized, placebo-controlled trial (NCT03612856) enrolling 24 patients of ESRD on hemodialysis, two different doses of xisomab (0.25 and 0.5 mg/kg) were tested [20]

This bioinspired strategy that can mimic the proton/electron transfer properties of natural enzymes to overcome the cellular redox imbalance may offer a hopeful route to develop antioxidase-like biocatalysts for treating a broad range of inflammation-associated diseases, such as arthritis, diabetic wounds, enteritis, and bone fractures

Microglial subgroups in the cerebral cortex after COVID-19 death were also evidenced

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