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Moreover, since the proximal part of the large intestine, particularly the cecum, has the highest rate of calcium uptake compared to other intestinal segments, and since surgical removal of the cecum can cause osteopenia in rats [9295], it is hypothesized that the DM-induced impairment of calcium transport across the large intestine would substantially contribute to impaired calcium metabolism and diabetic osteopathy
J Diabetes Metab Disord (2021) 20:161519
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