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Some agents may have clear mechanisms of action such as vitamins and dietary supplements like pyridoxine or omega-3 fatty acids however there is limited data on the use of dietary supplements in the treatment of dermatologic conditions such as acne [4]

Compared to the time-dependent moderate reduction in the IL&aC@RBAH group (mixture of IL-12 and aCTLA-4 in RBC) due to the pore formation on RBC, the majority of IL-12 content still remained at the tumor site on 3 days post-injection in the IL/aC@RBAH group, possibly attributed to the excellent hydrogel stability and effective IL-12 anchorage on the RBC surface

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This phenomenon may explain the profound immunosuppressive effects of MSCs on virtually any component of the immune system