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This has been especially problematic during the COVID-19 pandemic, as the world has searched for pharmaceutical treatment options to improve survival and for vaccines to prevent the spread of this virus

Reactive O2 species molecules include peroxide (H2O2) and superoxide anions (O2 with unpaired electron) these molecules are very toxic to the cell
The Bottom Line The shift from adrenal fatigue to HPA axis dysregulation represents a more scientifically grounded understanding of how chronic stress affects the body

Ann Neurol 59, 912921.Google Scholar Martnez-Lapiscina, EH, Clavero, P, Toledo, E et al
