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The phosphoinositide 3-kinase (PI3K) class of intracellular enzymes is involved in multiple cell signaling pathways, including the well-studied PI3K-Akt pathway, and is involved in various cellular functions, such as cell growth, proliferation, and differentiation [15]

doi: 10.1016/j.jff.2022.104942 304 YasirM.SaraU

Although neither the mechanism nor the implications of these changes are well defined, the high GSH content makes cancer cells chemoresistant, which is a major factor that limits drug treatment

Dutasteride pharmacology
