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To surmount these challenges, researchers are investigating novel drug delivery strategies and drug carrier systems, including the utilization of nanoparticles as carriers for DSF, with the objective of enhancing its specificity and efficacy in tumor tissue
Knipfer et al, 2019)
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This work demonstrates that GLA-KO human iPSC kidney organoids phenocopy human Fabry nephropathy and reveals the role of glutathione (GSH) metabolism as a mechanism, as well as an adjuvant therapeutic option for Fabry nephropathy