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When a paracellular route is intentionally targeted, a brief and reversible opening of tight junctions is required in which calcium chelators can lower extracellular calcium and loosen cadherin complexes, and medium-chain fatty acids or bile salts can disturb membrane order and temporarily reorganize claudin and occludin

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[DOI] [PMC free article] [PubMed] [Google Scholar] 339.Wu Y., Chen H., Xuan N., Zhou L., Wu Y., Zhu C., Li M., Weng Q., Shen J., Zhang H., Zhang B., Lan F., Xia L., Xiong X., Li Z., Zhao Y., Wu M., Ying S., Li W., Shen H., Chen Z
