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doi: 10.1016/s0378-8741(99)00174-9

158,159 The second step requires the activated NLRP3 oligomerization to recruit caspase-1 via ASC adaptor, ultimately leading to proteolytic cleavage of pro-IL-1 and pro-IL-18 into their active forms

Microneedling infusion for body contouring

Collectively, following the SP@M treatment, oxidative stress, inflammatory response, and osteoclast differentiation were regulated, which restored the osteoimmunology homeostasis for RA alleviation
