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glutathione conjugation acetomenephin Frontiers Critical care toxicology for acetaminophen
Description
P.UtrejaP.TiwaryA
The Journal of Neuroscience, 29 (14), 45924604

On one hand, gut dysbiosis facilitates ferroptosis by affecting iron metabolic pathways, like blocking the synthesis and release of hepatic hepcidin and expression of the iron transporter FPN1 to inhibit iron efflux and causing systemic and local iron overload in joints, thus leading to ferroptosis in OA chondrocytes

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