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Intriguingly, a Western diet high in PUFAs can induce intestinal inflammation in mice lacking one allele of GPX4 in IECs, which implies that dietary PUFAs may be a trigger of GPX4-restricted mucosal inflammation phenocopying aspects of human CD (143)

Measurement of alcohol dehydrogenase (ADH) activity The ADH activity of the supernatant were measured using an Alcohol Dehydrogenase Assay kit (Abcam, Cambridge, UK)

Homocysteine is an amino acid naturally produced in the body that can increase inflammation and damage to blood vessels when elevated