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In depression, it is hypothesized that the regulation of ACTH and cortisol secretory activity are altered, along with impaired corticosteroid receptor signaling (250,251)

doi:10.1093/jn/130.5.1132 Bendich A, Langseth L

Neuropsychopharmacology 37, 19531962

The FDA has also approved the following IL-23 blockers to treat plaque and other types of psoriasis: guselkumab (Tremfya) tildrakizumab (Ilumya) risankizumab (Skyrizi) Interleukin-17A blockers IL-17A is another protein that appears to trigger an immune system reaction that can lead to psoriasis
