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First, the macrophages were divided into 10 clusters, of which 4 clusters (clusters 2, 4, 5, 7) steadily decreased, and 3 clusters (clusters 0, 3, 8) increased after CD5/ LNP-FAPCAR 2.2 treatment
Cells 12 , 521 (2023)
In shuttle-saturated cells, reduced flux of pyruvate through the pyruvate dehydrogenase complex and the TCA cycle means less citrate is generated and exported from mitochondria
Nanoscale Horizons (2020) 5(8):121325
