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Veldhuis JD, Evans WS, Bowers CY, Anderson S

For researchers developing small-molecule inhibitors, nucleic acid therapeutics, uricosuric agents, or anti-inflammatory biologics, choosing the right animal model can directly influence the interpretability and translational value of preclinical data

This is the one universally-cited absolute contraindication across the peptide safety literature

Findings observed in laboratory investigations should not be interpreted as evidence of therapeutic efficacy, clinical utility, or approved medical applications
