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Some enzymes genetically break it down better than others (one of the reasons some handle alcohol than others.) This alcohol breakdown in the liver creates molecules that can lead to the production of reactive oxygen species (ROS) free radicals - tiny, very active molecules that contain oxygen

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Meftah et al., 2020)

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Morphine protects SH-SY5Y human neuroblastoma cells against Dickkopf1-induced apoptosis

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Bardoxolone methyl activated the Nrf2-Keap1-ARE pathway, potentially leading to an increase in GLO I expression and protecting kidney function in diabetic kidney disease [154]

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