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The final conjugation step is crucial in PDC synthesis

Dziadkowiec KN, Gasiorowska E, Nowak-Markwitz E, Jankowska A (2016) PARP inhibitors: review of mechanisms of action and BRCA1/2 mutation targeting

It was demonstrated that the percent of the survival effect of 5-FU/LV maintained was at least 61% for Study 2 and 10% for Study 1
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