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Antibiotic-manufacturing sites are hot-spots for the release and spread of antibiotic resistance genes and mobile genetic elements in receiving aquatic environments
Therefore, these patients should increase their daily fluid intake (2.53 L/day) by consuming water, milk, fruit juice, broth, sports drinks, coffee, and tea
The high throughput screening campaign of the substance library provided several hit compounds one of those the drug-like aryl sulfonamide 40 that was subsequently optimized into 41 that is a metabolically stable and reversible IRAP inhibitor
