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Finally, current evaluation parameters for musculoskeletal health are still not specific enough, and more accurate measurements of muscle mass/function and bone structure are needed to strengthen our ability to examine the relationship between vitamin B12 and musculoskeletal health

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Additional recent technical advances that provide insights into the impact of brain-derived alcohol metabolism are the generation of pre-clinical models that allow the investigation of cell-type-specific ALDH2 distributions in a brain-region-specific manner (139)