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The catalase inhibitors used, 3-amino-1H-1,2,4-triazole (3-AT) and sodium azide (NaN3), inhibited the removal of hydrogen peroxide by bovine catalase at a high rate in in-vitro experiments
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This Perspective discusses the emerging cellular roles of lysine lactylation, with a focus on the lactyl-CoA-independent pathway, and highlights the potential strategies of targeting lactylation for the treatment of associated human diseases.
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