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However, research has recently generated antigens and antibodies that will pave the way for immunoassays for SAMe and related molecules [187]

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The dominant study model types across the field are C57BL/6 depilation models (in which mouse body hair is shaved and the rate and quality of regrowth is measured), ex vivo human hair follicle organ cultures (in which individual follicles removed during cosmetic surgery are maintained in laboratory culture and their cycling behavior is observed), and in vitro cultures of human dermal papilla cells or hair follicle stem cell populations

To identify POMC neurons and GLP-1 receptor-positive neurons, POMC humanized Renilla green fluorescent protein (hrGFP) (The Jackson Laboratory, 006421) and GLP-1 receptor cre::tdTomato (The Jackson Laboratory, 029283) mice were used