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The key reaction of this downregulation is the phosphorylation of the intracellular (or cytoplasmic) receptor domain by protein kinases
Feeding responses of Zucker fatty rat to 2-deoxy-D-glucose, norepinephrine, and insulin
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Prof Adam Taylor, from Lancaster University, said potential benefits in pre-clinical studies such as those in animals and cells do not necessarily mean a peptide is beneficial for humans
