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This overall reaction is catalyzed by the enzyme glucose-6-phosphate dehydrogenase

doi: 10.4103/jcrt.JCRT_862_16 165 GonzalezACasadoJChuecaESalillasSVelazquez-CampoyAEspinosa AngaricaVet al

The Endogenous Decline Argument Plasma GHK falls from approximately 200 ng/mL at age 20 to approximately 80 ng/mL at age 60 in human cohorts 1 2
