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doi: 10.1080/08916934.2023.2259123 189
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Carica papaya extract stimulates Nrf2 in a mechanism that depends on the interaction of the Carica papaya flavonoids with the Nrf2 binding pocket of keap-1, leading to release of Nrf2 and its nuclear accumulation (Kumar et al., 2024)
54 Furthermore, it has been demonstrated that dysregulated glutathionylation processes contribute to the etiology of numerous human illnesses, such as lung, 55 neurological, 56 , 57 cardiovascular, 58 cataract, 59 and liver disease
