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Description
The protein encoded by the isoform 3 mRNA lacks 227 amino acids that are present in the central region of the protein encoded by the isoform 1 mRNA
To confirm Andexxas clinical benefit AstraZeneca used data from the Phase IV ANNEXA-I study, which found that the drug could induce significantly better hemostasis in patients with acute intracranial bleeding than usual care
doi: 10.1172/JCI117615
Additionally, both the shear and normal stresses decrease linearly from a depth of 5 km to the surface, reaching zero at the surface
