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Here, the previously determined rAmy-AMY 2 R-Gs was highly dynamic at the extracellular side, transitioning between the consensus (bypass) AMYR conformation and a CT-like conformation (Fig

Briefly, total RNA from cells was isolated using a Pure link RNA Mini kit (Life Technologies, USA), according to the manufacturers protocols

Studied in models involving connective tissue biology, cartilage-associated signaling, extracellular matrix pathways, and cellular regulation