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No toxic metabolites
Targeting of chondrocyte plasticity via connexin43 modulation attenuates cellular senescence and fosters a pro-regenerative environment in osteoarthritis

Augusto-Oliveira, M
Nevertheless, as the unnecessary side effects of intravenous NGF on the peripheral nerve are limited by its low stability, short half-life, and high cost (89, 90), it is not encouraged to try exogenous NGF in humans (91)
