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10.3389/fnagi.2019.00311 48 ChangH

The homocysteine-inducible, endoplasmic reticulum (ER) stress-inducible, ubiquitin-like domain member 2 (HERPUD1) in cultured HELA cells facilitate cytoprotective effects against oxidative stress by suppressing the inositol 1,4,5-triphosphate receptor and reducing the transfer of calcium ions from the endoplasmic reticulum to mitochondria [41]

In a multi-center ring study by Augustyniak et al

Pre-existing conditions like peripheral neuropathy or heightened skin reactivity may amplify sensations, though serious reactions remain uncommon in clinical settings
