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The needle used is very fine, so the sensation is typically just a tiny pinch that lasts for only a second

The regulatory effect of GPX8 on Ca 2+ may be related to the inositol 1,4,5-triphosphate receptor (IP3R) effect, and the transmembrane domain (TMD) of GPX8 is thought to play a key role in the regulation of Ca 2+ signaling (Yoboue et al., 2017)

3.2.3 PINK1 PINK1 is a serine/threonine protein kinase localized in mitochondria
